Karl-Friedrich BECKER - BIOBANQUES May 18, 2016


Biobanking National Infrastructure Meeting

Quality matters: Improving the quality of biological resources

Session 1: Controling Pre-analytical factors


Karl-Friedrich BECKER

Using tissue samples for quantitative protein and phosphoprotein analysis – critical considerations

Proteomics methods are very slowly or not at all translated into current clinical workflows for tissue analysis. Collecting human tissue samples is a complex process that varies between hospitals or even within single institutions.  Standardization of the entire workflow from test ordering to the report of the proteomic assay, with special emphasis on the pre-analytical phase, is crucial for successful integration of proteomic studies in the clinic as protein and phosphoprotein profiles may change due to sample processing before the analytical test is performed. The goals of personalized medicine to offer more effective drugs to patients cannot be reached until the research community, funding organizations, journal editors, biobanks managers, in vitro diagnostic developers, and many others adopt and follow common international standards. The aim of this presentation is to highlight the progress of proteomic studies with human tissues and to discuss the challenges that must be understood and addressed for successful integration of proteomics methods to clinical practice.?

TUESDAY MAY 17, 2016



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